The enzyme
ornithine decarboxylase (PDB
7odc (
http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=7odc), E.C. 4.1.1.17) is a homodimer of 461 amino acids (in humans, at least) that
catalyzes the decarboxylation of
ornithine producing, as a result, diamine
putrescine. This is the first step and the rate limiting step in humans for the production of
polyamines, compounds required for cell division.
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- Further information
- Ornithine decarboxylase
- http://herkules.oulu.fi/isbn9514266315/html/